BIOL 464/GEN 535

Population and Quantitative Genetics Schedule

Fall 2015

 

 

HOME - SCHEDULE -  LABORATORY - BACKGROUND READING

Note: Most unattributed figures and tables in lecture notes are from Hedrick (2011) or Hamilton (2009)

 

Day Date Topic Reading (from Hedrick 2011, unless otherwise specified)

M

Aug 17

Course Introduction  ppt pdf

 Ch1, 1-30; Rodgers-Melnick 2011

W

Aug 19

Lab 1: Class Intro. and Review of Probability 


F

Aug 21

Introduction to Genetic Variation  ppt pdf

Solution to Hair and Eye Color Problems
 Ch 1, 30-38

M

Aug 24


Allele Frequencies and Hardy-Weinberg  ppt pdf

Ch 2, 65-78; 82-92

W

Aug 26

Lab 2: Hardy-Weinberg Equilibrium  

F

Aug 28

Assaying Genetic Variation  ppt pdf

Ch 1, 38-48

M

Aug 31
Measures of Genetic Variation and Inbreeding ppt pdf

Merle Calculation
 Ch 2, 92-107

W

Sep 2

Lab 3: Genetic Variation

 

F

Sep 4
Inbreeding ppt pdf Ch 8, 441-478

M

Sep 7

Labor Day-No class


W

Sep 9

Lab 4: Inbreeding and Kinship

 

F

Sep 11

Introduction to Selection ppt pdf

Ch 3, 111-131

M

Sep 14

Types of Selection ppt pdf

Ch 3, 131-148

W

Sep 16

Lab 5: Selection 

 

F

Sep 18

Selection in Real Populations ppt pdf

Kuru Hardy-Weinberg calculation
Ch 3, 159-183

M

Sep 21

Review

Review Slides ppt pdf

2010 Exam and Answer Key

Formula Sheet

 

W

Sep 23

Exam 1

Answer Key and Excel

 

F

Sep 25

Introduction to Genetic Drift ppt pdf

Ch 4, 187-205

M

Sep 28

Effective Population Size ppt pdf

Ch 4, 205-242

W

Sep 30

Lab 6: Drift and Effective Population Size

 

F

Oct 2

Population Structure ppt pdf

Ch 7, 368-392

M

Oct 5

Population Structure and Assignment Tests ppt pdf

 Ch 7, 392-412

W

Oct 7
Lab 7: Estimating Population Structure  

F

Oct 9
Likelihood and Genetic Identity ppt pdf Ch 8, 492-499; Woods 1999

M

Oct 12

Fall Break


W

Oct 14
Lab 8: Individual Identity and Population Assignment
 

F

Oct 16

Parentage Analysis ppt pdf

Ch 8, 480-492; Jones 2010

M

Oct 19

Linkage Disequilibrium Introduction ppt pdf

Ch 9, 523-540

W

Oct 21
Lab 9: Linkage Disequilibrium  

F

Oct 23

Causes and Consequences of Linkage Disequilibrium ppt pdf

Ch 9, 540-552; 563-587

M

Oct 26

Review Summary,  and Lecture ppt pdf

Review Calculations

Blank 2014 Exam, Answer Key, and Excel Sheet

Formula Sheet


W

Oct 28
Exam 2 Answer Key Excel Sheet
 

F

Oct 30
Mutation ppt pdf

Mutation and Mating Simulation
Ch 5, 247-293

M

Nov 2
Introduction to Neutral Theory ppt pdf  Ch 6, 295-315

W

Nov 4

Lab 10: Mutation

 

F

Nov 6

Tests of Neutrality ppt pdf


Ch 6, 316-341

M

Nov 9

Phylogenetics and Phylogeography ppt pdf

Tree Quiz


Ch 6, 341-347; Ch 7, 412-424

W

Nov 11

Lab 11: Detecting Departures from Neutrality

 

F

Nov 13
Coalescence ppt pdf Ch 6, 347-361

M

Nov 16
Human Evolutionary History ppt pdf Svante Pääbo NIH Lecture

W

Nov 18

Lab 12: Phylogenetics and Coalescent Analysis

 

F

Nov 20
Quantitative Traits ppt pdf Ch 1, 57-63

M

Nov 23
Thanksgiving Break

W

Nov 25
Thanksgiving Break  

F

Nov 27
Thanksgiving Break
 

M

Nov 30
QTL and Association Genetics ppt pdf Ch 9, 587-596; Visscher 2012

W

Dec 2
Lab 13: Association Genetics and Course Evaluations  

F

Dec 4
Review Summary

M
Dec 7

Final Exam

Formula Sheet

2015 Answer Key

2015 Excel Calculations

Exam will be 50 minutes in 3306 LSB (computer lab)