BIOL 464/GEN 535

Population and Quantitative Genetics Schedule

Fall 2011

HOME - SCHEDULE - LABORATORY - BACKGROUND READING

Text: Hamilton, Matthew B. 2009. Population Genetics. Wiley-Blackwell, Chichester, Sussex.

Note: Most unattributed figures and tables in lecture notes are from the Hamilton text or Hedrick (2005)

Day	Date	Topic	Reading (from Hamilton 2009, unless otherwise specified)
M	22-Aug	Class Introduction and Probability ppt pdf	Preface; Ch 1; Appendix pp. 376-380
W	24-Aug	Lab 1: Review of Probability
F	26-Aug	Introduction to Genetic Variation ppt pdf	Ch 2, pp. 9-12
M	29-Aug	Allele Frequencies and Hardy-Weinberg ppt pdf	Ch 2, pp. 13-22
W	31-Aug	Lab 2: Hardy-Weinberg Equilibrium
F	2-Sep	Hardy-Weinberg Equilibrium and Genetic Variation ppt pdf	Ch 2, pp. 22-29
M	5-Sep	Labor Day-No Class
W	7-Sep	Lab 3: Genetic Variation
F	9-Sep	Genetic Variation and Inbreeding ppt pdf Ne and Chi-Square Calculation	Ch 2, pp. 29-32
M	12-Sep	Inbreeding ppt pdf	Ch 2, pp. 33-41
W	14-Sep	Lab 4: Inbreeding and Kinship
F	16-Sep	Introduction to Selection ppt pdf	Ch 6, pp. 185-197
M	19-Sep	Types of Selection ppt pdf	Ch 6, pp. 197-207
W	21-Sep	Lab 5: Selection
F	23-Sep	Mutation ppt pdf	Ch 5, pp. 154-166; Ch 8, pp 274-281
M	26-Sep	Review 2010 answer key word pdf Formula Sheet
W	28-Sep	Exam 1 Answer Key
F	30-Sep	Genetic Drift ppt pdf	Ch 3, pp. 53-73
M	3-Oct	Effective Population Size ppt pdf	Ch 3, pp. 73-87
W	5-Oct	Lab 6: Effective Population Size
F	7-Oct	Population Structure ppt pdf	Ch 4, pp. 105-111; 118-142
M	10-Oct	Bayesian Inference of Population Structure ppt pdf Linanthus Calculation	*Pritchard et al. 2000
W	12-Oct	Lab 7: Population Structure
F	14-Oct	Population Assignment ppt pdf	Ch 4, pp. 111-118; *Jones 2010
M	17-Oct	Likelihood and Genetic Identity ppt pdf	Ch 2, pp. 19-24; Hedrick Ch 11, pp. 636-650; *Woods et al. 1999
W	19-Oct	Lab 8: Individual Identity and Population Assignment
F	21-Oct	Paternity Analysis ppt pdf	Hedrick Ch 11, 597-621
M	24-Oct	Phylogenetics and Phylogeography ppt pdf Tree Quiz	Hedrick Ch 11, 646-650
W	26-Oct	Lab 9: Phylogenetic Analysis
F	28-Oct	Coalescence ppt pdf	Ch 3, pp. 87-103; Ch 4, pp. 142-150
M	31-Oct	Review Formula Sheet
W	2-Nov	Exam 2 Key Excel key
F	4-Nov	Human Evolutionary History ppt pdf	*Garrigan and Hammer 2006; Briggs et al. 2009; Green et al. 2010
M	7-Nov	Introduction to Neutral Theory ppt pdf	Ch 8, pp. 235-250
W	9-Nov	Lab 10: Coalescent-Based Analysis
F	11-Nov	Tests of Neutrality ppt pdf	Ch 8, pp. 250-274
M	14-Nov	Linkage Disequilibrium Introduction ppt pdf	Ch 2, pp. 41-50
W	16-Nov	Lab 11: Detecting Departures from Neutrality
F	18-Nov	Causes and Consequences of Linkage Disequilibrium ppt pdf	Ch 8, pp. 274-281
M	21-Nov	Thanksgiving Recess
W	23-Nov	Thanksgiving Recess
F	25-Nov	Thanksgiving Recess
M	28-Nov	Quantitative Genetics ppt pdf	Ch 9, pp. 283-303
W	30-Nov	Lab 12: Linkage Disequilibrium
F	2-Dec	QTL and Association Genetics ppt pdf	Ch 9, pp. 315-330
M	5-Dec	Advanced Association Genetics ppt pdf	*Balding 2006
W	7-Dec	Lab 13: Association Genetics and Course Evaluations
F	9-Dec	Review 2010 Final (blank) 2010 Final Answer Key 2010 Excel Calculations Formula Sheet
W	14-Dec	Final Exam at 11 am in 3131 LSB Answer Key Bring a calculator!

*Username and password for selected readings are on the course syllabus at the bottom of the schedule