Biology 493V-001, Spring 2007
Mondays, Wednesdays & Fridays, 10:30-11:20 PM
Rm. 3306 LSB (computer lab)
CONTACT INFORMATION
Lecturer: Dr. Jane Caldwell
Phone: 293-5201 Ext. 31459
Office: 3324-A LSB (3rd floor, at rear of General Biology
labs suite)
E-mail:
Office Hrs.: Tuesday 3:30-5:00 PM, Wednesday 3:30-5:00 PM,
Friday 1:00-2:00 PM, or by appointment
Drop in visits are welcome, although I may not always be available immediately.
REQUIRED MATERIALS
Textbook: Introduction
to Protein Structure, 2nd edition; Carl Branden
& John Tooze (© 1999, Garland Science)
Software: Swiss-Protein
PDB Viewer (“spdbv” or “DeepView”:
freeware for Mac or PC, on your own computer or in LSB computer lab; details
will be discussed in class)
Websites: WVU
eCampus (
MIX: http://mix.wvu.edu (email)
Syllabus: http://www.as.wvu.edu/~caldwell/493v.htm
CLASS POLICIES
Attendance: Your
attendance and active, thoughtful participation will be an important part of
each class meeting. If you must miss a
class, you will need to make arrangements with a classmate to borrow
notes. Most hands-on activities done in
class cannot be made up, and homework due in class cannot be handed in
late. (If you are a senior and will miss
class for job or grad school interviews, please come
talk with me so we can agree on a plan for missed work.)
Computers: You
will need access to your MIX and eCampus (a.k.a. WebCT or
Much
of our class will be based around observations and measurements of actual
protein structures using specialized software.
This software will be installed on computers in the LSB computer lab;
however, hours of access are limited. If
at all possible, I suggest you download and install this free software on your
own computer; ask me if you need help. I
will hand out more details in class.
Homework: Reading
assignments on the attached syllabus should be completed before each class; class discussions
will depend heavily on your input and questions. Some days one or two students will be
responsible for leading discussions!
Homework
problems will be assigned approximately every 1 to 1½ weeks. I expect you to work through all of these
problems, and to bring your answers to class.
Some problems will be discussed (by you and all classmates) in class,
and several problems from each assignment will be graded. Other assignments will be announced as the
semester progresses. These short
homework assignments will count for 20% of your grade.
I
encourage group work outside of class, as long as each individual is learning
all topics thoroughly and doing all parts of each assignment. If you discuss a homework problem with
another person, please cite them at the end of your answer: “I talked with Kim about this problem,” or
“Dave showed me how to do this calculation on the computer,” etc. Even if you work together, your answers must
be thought through and written down independently; identical answers will
receive a zero.
Projects: As
we progress through the semester, you will do some “mini-projects” that will
let you practice what you have learned.
Most projects will focus on producing diagrams on the computer as well
as describing and explaining protein structures, and are more substantial that
ordinary homework. You will be given
several days to do each mini-project.
You will generally place those diagrams in PowerPoint and hand them in
using eCampus.
Near
the end of the semester, you will complete a “major project” that lets you
apply all you’ve learned to a specific protein.
Choose any protein that interests you, so long as it has a known,
experimentally determined structure not already discussed in class or your textbook. You
will write a 10-15 page paper, make your own diagrams and measurements using
the software we have mastered in class, and give a 15-20 minute presentation in
class.
All
these projects together will count for 30% of your grade. At least half of these points will come from
your “main project.”
Tests: You
will have 2 tests (50 pts each), and a final exam (50 pts). Tests will cover a combination of material
from lectures, texts, and homework, and occasional hands-on tasks using the
structure-viewing software.
Occasional
short, unannounced “pop” quizzes will be given to ensure that you are keeping
up. These will generally be worth 5
points.
Absences: For
regular class meetings, you will be responsible for any material or points you
miss. Homework assignments cannot be
handed in late, and hands-on activities cannot be made
up, unless arrangements are made with me in advance.
If
you miss an exam, you will receive a zero.
If you have a valid,
verifiable excuse,** contact me within 24
hours to schedule a make-up test. My voice mail is always
available—please call rather than sending e-mail! Your exam will be graded AFTER I verify your
excuse.**
** Only
serious, valid excuses will be considered such as funerals of immediate
family members, severe illness, injury, or similar serious issues. I will determine the validity of all
excuses. When possible, please do find a
reliable, trustworthy person to confirm that you could not possibly attend the
scheduled exam—this does not need to be a doctor or healthcare
professional. Most problems can be
resolved by talking with me in person.
Athletes and others, take
note:
If you are required miss an exam for a scheduled WVU event, please
contact me at least a week in advance to arrange a make-up time.
Grading: Your
grade will be based ONLY on the points you earn during the semester; no
extra credit will be given to individuals.
Tests
& Quizzes 50% Grading
Scale¥: 90-100% = A
Homework 20% 80-89% = B
Projects
(Major and Mini) 30% 70-79% = C
Total 100% 60-69% = D
0-59% = F
I
do assign plusses and minuses to grades, although these do not affect your GPA.
To
calculate your grade, you will need to know the percentage you have earned so
far for each portion of the semester:
Grade
= 0.3(% Projects) + 0.2(% on Homework) + 0.5 (% on Tests)
Cheating: Please
don’t waste my time and yours by cheating.
I expect all work handed in to be the direct result of your independent
thought and effort; any assignments that vary from this expectation will
receive a zero. More than one incidence
of cheating on homework or other assignments, or any type of cheating on an
exam will result in a grade of F for the course and written notice of academic
dishonesty to the Biology Department and the Dean’s Office.
Evacuation: In
the case of a fire drill or actual emergency, collect your belongings and walk
calmly to the stairwells at either end of the building. (The central glass stairwell is not
considered a fire exit.) After descending
the stairs and exiting, please cross
Social
Justice Statement:
Please
tell me as soon as possible if you have a disability and need special
accommodations. You will need a letter from Disability Services
(293-6700); even if your letter is delayed, please see me at least one week
before the first exam. All information will be kept confidential,
and arrangements will be made discreetly.