Lecture 25:  Respiratory System - Gas Exchange & Transport

Sherwood: Chapter 11

Objective:  The ultimate purpose of breathing is to provide a continual supply of fresh oxygen for pickup by the blood and to constantly remove carbon dioxide unloaded from the blood.

1.  Respiratory cycle
        a.  alveolar ventilation
        b.  pulmonary ventilation
2.  Partial pressure gradients
3.  Fick’s Law of Diffusion
4.  Oxygen transport
        a.  physically dissolved in hemoglobin
        b.  chemically bound to hemoglobin
5.  Oxygen-hemoglobin dissociation curve
        a.  Bohr effect
        b.  temperature
        c.  2,3,-diphosphoglycerate
6.  Carbon dioxide transport
        a.  physically dissolved
        b.  bound to hemoglobin
        c.  as bicarbonate
        d.  Haldane effect