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In
vitro selection, molecular recognition elements:
DNA and peptide, nanomaterials, evolution of
bacteria Research
in the Sooter Lab centers around methods of in
vitro selection.
These methods are used to create molecular
recognition elements (MRE’s), or binding species,
that have high affinity and specificity for a
particular target.
DNA or amino acids are the building blocks of
the MRE’s in this lab.
As part of WVNano, nanomaterials are the
primary targets.
By combining biology with materials science,
novel methods of detection may be created.
Evolution of different bacteria is also a research
focus. E. coli and Deinococcus
Radiodurans are exposed to defined types of
radiation which are present on the Martian surface.
Gradual selective pressure is applied and
bacteria with a new phenotype are isolated.
The whole genomes of isolates are sequenced
and analyzed. These
new bacteria may one day provide a rich food source
for astronauts working on Mars.
Dr. Sooter's Home Page: www.sooterlab.org
WVNano
homepage: wvnano.wvu.edu
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