Plant Genomics, Molecular
Ecology, Plant Population Genetics, Biotechnology
Risk Assessment
My overall research
goal is to use the power of genomics to gain
enhanced understanding of natural ecosystems. Trees
from the genus Populus are premier model
organisms for studies of adaptive molecular
variation, because
abundant genetic resources are available,
including a whole genome sequence, and Populus
plays a dominant role in many important ecosystems.
I am actively involved in the Populus genome
sequencing project, as well as sequencing projects
for other species that are associated with
Populus in wild populations. As our knowledge
of the function of individual genes increases, and
high-throughput genotyping techniques continue on
their rapid pace of development, it will become
possible to characterize molecular variation in
natural populations and map adaptive diversity on a
landscape scale.
I
am also interested in functional genomics of
Populus and other species with the ultimate goal
of enhancing economic and environmental utility. For
example, I am currently involved in several
projects aimed at enhancing the carbon
sequestration potential of Populus by
identifying genes involved in allocation and
partitioning of carbon. I believe that multiple
approaches are required for gene discovery and
characterization in forest trees, and that
biotechnology will have drastic effects on tree
improvement and large-scale silviculture.
As
biotechnological methods continue to develop, and
transgenic trees approach commercialization, there
will be a great need to devise strategies to assess
ecological risks and monitor environmental impacts.
I use a combination of molecular and simulation
modeling approaches to help assess potential risks
posed by transgenics. I am also interested in
applying similar methods to assessing the threat
posed by the introduction and spread of exotic
organisms.
Dr. DiFazio's Home Page:
http://www.as.wvu.edu/~sdifazio/ |